Rebuild your skin’s vitality with Plinest® — deep regeneration, not just surface glow.
Plinest® – Skin Regeneration & Collagen Repair Therapy
The Technology Behind Plinest®
Understanding the Science of Plinest® — How It Strengthens, Repairs, and Revives Skin
Plinest® is formulated with PN‑HPT™ (Polynucleotides – Highly Purified Technology) — DNA fragments derived from trout, specially purified to a high pharmaceutical standard.
These polynucleotides work at a cellular level to stimulate fibroblasts, boost collagen synthesis, and encourage tissue repair.
Over time, this leads to improved skin elasticity, firmer texture, and better hydration.
How Plinest® Works:
-
Activates fibroblast cells to produce more collagen and elastin, strengthening skin structure.
-
Supports skin regeneration and repair, reducing visible damage and improving resilience.
-
Enhances deep dermal revitalization/repair, restoring a plump, supple appearance.
-
Exhibits anti-inflammatory and antioxidant effects to calm skin and reduce stress‑related damage.

Plinest® Range Variations Available at Dr. A Clinic

Plinest® Fast
For Delicate Areas, Dark Circles & Fine Lines
Plinest® Fast is a lighter, fast-acting formulation of Plinest® designed specifically for delicate areas such as the under-eye region. While not as concentrated as the standard Plinest®, it helps reduce fine lines, improve skin texture, and lighten dark circles, providing a refreshed and youthful appearance.
Benefits of Plinest® Fast:
✔ Smooths fine lines around delicate eye areas
✔ Reduces dark circles and fatigue signs
✔ Improves eye area skin texture and hydration
✔ Gentle yet effective for sensitive eye areas
Why Choose Dr. A Clinic for Plinest® Therapy
Regenerative Expertise
Our certified aesthetic doctors are experienced in advanced polynucleotide treatments, ensuring high-precision and safe delivery for optimal skin repair.
Tailored Treatments
Our doctors customise treatment plans to suit your skin type and goals, whether it’s for pigmentation concerns or skin rejuvenation.
Authentic Formulation
We use genuine PN‑HPT™ Plinest® imported from Mastelli (Italy), backed by decades of research and designed for deep tissue bio‑regeneration.
Choose Plinest® at Dr. A Clinic to regenerate your skin deeply — for more luminous, stronger, and youthful-looking skin.
Frequently Asked Questions
❓What is PN‑HPT™?
PN‑HPT™ stands for “Polynucleotide – Highly Purified Technology.” These are highly purified DNA fragments derived from trout, processed using Mastelli’s patented method for maximum safety and effectiveness.
❓How many sessions do I need?
A typical course is 3–6 sessions, spaced a few weeks apart, followed by periodic maintenance.
❓Is Plinest® safe for pigmentation like melasma?
Yes — Plinest® helps improve skin quality, texture, and repair. It can be an excellent adjunct to other melasma treatments (e.g. PICO laser) for better long-term skin health.
❓What are the possible side effects?
Common mild effects include redness, swelling or bruising at treated areas, which typically resolve within a few days.
❓When will I see results?
Initial improvements in hydration and skin texture may appear within weeks, while fuller collagen‑remodelling effects develop over a few months. Clinical studies show measurable gains in elasticity and skin quality.
❓Can Plinest® be combined with other treatments?
Absolutely. Plinest® is often used alongside lasers, microneedling, or other skin booster treatments to enhance healing and boost long-term skin regeneration.
